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Cordyceps Extract Powder
Cordyceps militaris — a medicinal mushroom with centuries of use in traditional Chinese medicine. Primary bioactive: cordycepin (3′-deoxyadenosine), an adenosine analog with documented pharmacological effects across multiple systems [1]. Standardized to ≥30% polysaccharides. Enhances cellular bioenergy status via ATP production pathways [2].
Mechanisms of Action
Cordycepin — Adenosine Analog Pharmacology
Cordycepin (3′-deoxyadenosine), the primary bioactive metabolite, demonstrates diverse pharmacological effects including immunomodulatory, hepatoprotective, and anti-inflammatory properties. Unique adenosine analog structure enables interaction with multiple cellular signaling pathways [1].
ATP & Bioenergy Enhancement
Improves steady-state bioenergy status: hepatic ATP increased by 18.4% and ATP:Pi ratio by 47.7% in treated subjects. Mechanism underlying clinical effectiveness in alleviating fatigue and improving physical endurance [2].
Anti-inflammatory — TLR4/NF-κB Pathway
Cordycepin suppresses pro-inflammatory mediators (NO, PGE2) by inhibiting iNOS and COX-2 expression. Inhibits TLR4 binding, MAPKs phosphorylation, and NF-κB nuclear translocation [5].
Hepatoprotective — AMPK Activation
Cordycepin attenuates hepatic steatosis, inflammation, and fibrosis via AMPK phosphorylation-dependent signaling. Reduces hepatic triglyceride accumulation and inflammatory cell infiltration [6].
Neuroprotective — White Matter Preservation
Long-term neuroprotection via suppressing neutrophil infiltration, preserving blood-brain barrier integrity, and promoting anti-inflammatory microglial polarization. White matter integrity preserved across morphology, histology, ultrastructure, and electrical conductivity [7]. Bioactives show potential against Alzheimer’s, Parkinson’s, and ALS [16].
Blood Glucose Regulation
47% reduction in blood glucose, 214% increase in hepatic glycogen content. Significant improvement in oral glucose tolerance. Protective effects against diabetes-related kidney and spleen injury [8].
Immune Modulation & Anti-Allergic
Polysaccharides demonstrate immunomodulatory properties. Fermented Cordyceps suppresses IgE-mediated mast cell activation and type I hypersensitive allergic responses [9,4].
Polysaccharide Bioactivity
Rich in β-glucans, polysaccharides, polyphenols, and ergosterol. Functional components play roles in antioxidant, anti-inflammatory, anti-obesity, and immune system regulation [10].
Sport & Endurance Applications
Traditional use as an endurance performance enhancer. Bioactive compounds including cordycepin and adenosine support energy metabolism and physical performance capacity [3].
Net Weight: 1kg (1000g)
Format: Extract Powder
Cordyceps militaris Extract
Polysaccharides: ≥30%
Extraction: Hot Water Extract
Origin: EU GMP Certified (Austria)
No fillers, no additives, no excipients. 100% pure extract powder.
Suggested Use: Dissolves in liquids, hot and cold. Stir into water, tea, coffee, juice, or smoothie. Suitable for baking and functional food recipes. 1–2g daily or as directed by a healthcare professional.
Allergens: No common allergens. No synthetic colors, flavors, or preservatives. Non-GMO.
Safety: Consult a physician if pregnant, breastfeeding, or taking any medication. Do not use if you have mushroom allergies. Not a substitute for a varied diet. Keep out of reach of children.
Mix one teaspoon into your favorite drink or food, once or twice a day.
You will need: Mushroom extract powder, Teaspoon, Drink or food of choice.
- Measure. Use a clean spoon to take 1 teaspoon (about 2 grams) of the powder.
- Mix. Stir into water, juice, a smoothie, coffee, tea, yogurt, or any food. Dissolves easily in both hot and cold liquids.
- Consume. Drink or eat. Take 1–2 times per day, with or without food.
Tip: One 1 kg package provides approximately 500 servings. Store in a cool, dry place, sealed after each use.
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1. Properties of Cordyceps sinensis: A review. DOI
2. CordyMax Cs-4 improves steady-state bioenergy status in mouse liver. DOI
3. Herbal medicine for sports: a review. DOI
4. Cordyceps militaris fermented extract inhibits inflammatory reactions and alleviates contact dermatitis. DOI
5. Anti-inflammatory effects of cordycepin via TLR4-mediated suppression of MAPKs and NF-kB. DOI
6. Cordycepin ameliorates nonalcoholic steatohepatitis by AMPK activation. DOI
7. Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration after traumatic brain injury. DOI
8. Cordycepin from Cordyceps militaris prevents hyperglycemia in diabetic mice. DOI
9. Cordyceps militaris fermented extract suppresses IgE mediated mast cell activation and type I hypersensitivity. DOI
10. Effects of fungal feed additives in animals: a review. DOI
11. Enhanced production of cordycepin under solid-state fermentation of Cordyceps militaris. DOI
12. Cordyceps militaris polysaccharides: immune, antioxidant, anti-inflammatory activities. DOI
13. Adenosine deaminase inhibitory activity: boost cordycepin production in Cordyceps militaris. DOI
14. Cordycepin, a metabolite of Cordyceps militaris, reduces immune-related gene expression. DOI
15. Inhibition of cytokine expression by Cordyceps extract. DOI
16. Unique bioactives from Cordyceps as promising multitargeted neuroprotective agents. DOI
